Calm-PRT is a combination of ingredients designed to release stress and restore proper communication within the hypothalamic-pituitary-adrenal (HPA) axis. Calm-PRT contains an extract of the adaptogen Rhodiola rosea , a source of biologically-active rosavins. NeuroScience's Rhodiola is standardized to contain 16% rosavins, which have been found to decrease the effects of stress and fatigue.